(Encephalopathy, Hepatic; Portal-Systemic Encephalopathy; Encephalopathy, Portal-Systemic)
|Oxygen and Blood Flow to the Brain|
|If the liver is not working properly, toxins can build up in the blood. The toxic blood travels to the brain, affecting the brain's ability to function.|
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- Changes in behavior and personality
- Shortened attention span
- Depression or anxiety
- Slurred speech
- Tremor , particularly a flapping tremor of the hands
- Loss of consciousness
- Liver function tests
- Kidney function tests
- Imaging tests of the liver
Hospitalization and Emergency Care
- Neutralize toxins in the intestine such as ammonia
- Remove blood from the intestines
- Reduce ammonia production by intestinal bacteria
- Reduce the amount of ammonia producing bacteria
- Treat the condition that started the encephalopathy
- Reduce recurrence
- Get early treatment for liver problems.
- If you have a disease such as cirrhosis, see your doctor regularly.
- Follow your doctor's instructions regarding medication. Avoid overdosing.
- Avoid being exposed to poisons or toxins.
- Avoid excessive alcohol.
- Do not use IV drugs.
National Digestive Diseases Information Clearinghouse http://digestive.niddk.nih.gov
National Institute of Neurological Disorders and Stroke http://www.ninds.nih.gov
Canadian Liver Foundation http://www.liver.ca
Health Canada http://www.hc-sc.gc.ca
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4/2/2010 DynaMed's Systematic Literature Surveillance https://dynamed.ebscohost.com/about/about-us : FDA approves new use of Xifaxan for patients with liver disease. US Food and Drug Administration website. Available at: http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm206104.htm . Published March 24, 2010. Accessed April 2, 2010.