(Bile Duct Cancer; Cancer, Bile Duct)
- Intrahepatic—develops in the bile duct branches that are located in the liver
- Perihilar—develops at the point where the branches of the bile duct join and leave the liver (most common form)
- Distal—develops in the area of the bile duct that is closer to the small intestine
|Common Bile Duct|
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- Having a chronic condition that causes inflammation of the bile duct such as primary sclerosing cholangitis, ulcerative colitis , bile duct stones, choledochal cysts
- Cirrhosis of the liver or another condition that affects the liver or bile duct such as polycystic liver disease, Caroli syndrome
- Infection by parasites called liver flukes (more common in Asian countries)
- Age older than 65 years
- Overweight or obesity
- Exposure to a radioactive substance or toxic chemicals
- Family history of bile duct cancer
- Jaundice (yellowing of the skin and whites of the eyes)
- Abdominal pain
- Weakness, fatigue
- Decrease in appetite, weight loss
- Itchy skin
- Dark urine, pale stool
- Endoscopic retrograde cholangiopancreatography (ERCP)—x-rays and a long, flexible tube with a camera to examine the bile duct
- Angiography —x-rays of the blood vessels
- Laparoscopy —thin tube with a camera on one end to examine the bile duct
- Biopsy —a sample of the bile duct cells is removed and examined
- Intrahepatic bile duct cancer—may include the removal of part of the liver or an entire lobe
- Perihilar bile duct cancer—may include the removal of part of the liver, bile duct, and gall bladder
- Distal bile duct cancer—may include the removal of part of the pancreas and small intestine
- External radiation therapy—radiation directed at the tumor from a source outside the body
- Internal radiation therapy—radioactive materials placed into the body in or near the cancer cells
American Cancer Society http://www.cancer.org/
Cholangiocarcinoma Foundation http://www.cholangiocarcinoma.org/
BC Cancer Agency http://www.bccancer.bc.ca/
Canadian Cancer Society http://www.cancer.ca/
Bile duct cancer (cholangiocarcinoma). Johns Hopkins Medicine website. Available at: http://www.hopkinsmedicine.org/liver%5Ftumor%5Fcenter/conditions/bile%5Fduct%5Fcancer.html . Accessed June 18, 2013.
Bile duct cancer. American Cancer Society website. Available at: http://www.cancer.org/cancer/bileductcancer/index . Updated March 2, 2011. Accessed June 18, 2013.
Bile duct cancer. Cancer.net website. Available at: http://www.cancer.net/patient/cancer+types/Bile+duct+cancer . Updated February 2012. Accessed June 18, 2013.
Cholangiocarcinoma. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed/what.php . Updated April 22, 2013. Accessed June 18, 2013.
Cholangiocarcinoma. The Cholangiocarcinoma Foundation website. Available at: http://www.cholangiocarcinoma.org/definition.htm . Accessed June 18, 2013.
- Reviewer: Mohei Abouzied, MD
- Review Date: 12/2013
- Update Date: 01/13/2014